Roosters secure 'greatest win'

80 min: Tupou bumped To'o into touch as he dived for the corner on the last play of the match to secure a massive upset by the Roosters.

77 min: Cleary kicked another penalty goal to reduce the Roosters lead to just one converted try after Wong was penalised for being offside. Roosters 38-32

74 min: Casey McLean scored on the next set after Alamoti picked up a loose pass and shifted it to his unmarked winger but Cleary's sideline conversion attempt hit the upright and bounced out. Roosters 38-30.

73 min: Nathan Cleary kicked a penalty goal to put the Panthers within two converted tries of the Roosters after rookie Salesi Foketi was sent to the sinbin for a high tackle. Roosters 38-26

70 min: England winger Dom Young all but sealed the win when he finished a backline shift in the corner after Tedesco held up a pass to create an overlap. 38-24.

60 min: Kangaroos fullback Dylan Edwards limped from the field after pulling up lame from his attempt to chase down Smith.

56 min: Daniel Tupou scored his second try in the 53rd minute and Sandon Smith sprinted away to score three minutes later. Roosters 34-24.

48 min: The Roosters have conceded the most points in back to back matches in the club's 117-year history after Dylan Edwards scored for the Panthers to again draw the scores level. The previous record was 63 points in back-to-back matches but after conceding 50 points against the Broncos in Round 1 they have now exceeded that total. 

44 min: Watson got his second try of the match after backing up a James Tedesco break to score and put Roosters back ahead against the four-time premiers. 

39 min: Interchange forward Liam Henry raced through to snatch a Nathan Cleary kick under the posts and score. Panthers 18 Roosters 18.

37 min: Penrith's Test and Origin second-rower Liam Martin has been forced from the field for a HIA

35 min: Tongan winger Daniel Tupou put the Roosters back in front when he crossed in the corner and Sandon Smith nailed the sideline conversion. Roosters 18-12.

31 min: Superstar winger Brian To'o showed his individual brilliance to catch and drop the ball to his foot in one motion, then scramble over the tryline to reach out and score. 12-12.

9 min: The Roosters took the lead when hooker Connor Watson raced over to score from dummy half. Roosters 12-6.

6 min: Former Wallabies star Mark Nawaqanitawase levelled the scores for the Roosters after finishing an impressive ball movement. Panthers 6 Roosters 6

3 min: The Panthers got off to a flier when Paul Alamoti scored after Roosters second rower Siua Wong spilled an early kick. Panthers 6-0

'Anything can happen'

Nathan Cleary insists the Panthers won't be underestimating the Roosters, despite last weekend's 50-12 loss to the Broncos.

"It's such a great cub and has been for such a long time now," he told Fox League. "At their helm is James Tedesco, an absolute superstar of a player, so we definitely can't take them lightly and at this time of year anything can happen, so we really want to be focusing ourselves and playing well."

Late Mail

Panthers: A change 24 hours out from kick-off with back-rower Isaiah Papali'i dropping out, replaced by Liam Henry in his return from a shoulder injury. Brian To'o's return from a hamstring injury has triggered a backline reshuffle, with Paul Alamoti shifting to the centres and Luke Garner moving to the bench. Fellow winger Casey McLean suffered a head knock in Vegas but will line up thanks to the extended gap between games. Brad Schneider is 18th man.

Roosters: Local junior Hugo Savala is set to make his NRL debut after being promoted to the bench when Lindsay Collins dropped out on Thursday. The Origin forward has been rested after battling illness this week. Taylor Losalu will start the game at prop in jersey No.17. Centre Billy Smith will make his long-awaited return to the field via NSW Cup on Saturday, with coach Trent Robinson confirming Smith will drop out of the extended NRL squad. Victor Radley's absence due to the concussion protocol has also prompted a forward pack reshuffle, young gun Salesi Foketi stepping into the starting side and former Eel Makahesi Makatoa coming on to the bench. Ethan Roberts is 18th man.

Warriors v Sea Eagles at Go Media Stadium

The Warriors have bounced back from their first round loss in Vegas to defeat Manly 36-16 in a costly night for the Sea Eagles after losing captain Daly Cherry-Evans and Tom Trbojevic to injury.

The star duo came from the field late in the match and were unable to return, forcing Manly to play with 12 men for the last 15 minutes after Jake Trbojevic was sinbinned.  

Despite the return of Trbojevic from the sinbin, the Sea Eagles ran out of interchanges after losing Cherry-Evans and Tom Trbojevic.

Trbojevic, who suffered a tightening of his hamstrings, went into the dressing room and did not return, while Cherry-Evans was clutching at his back.

The Warriors had earlier overcome a poor start to fight their way to an 18-6 halftime lead and hung on as Manly mounted a second half comeback, with Cherry-Evans scoring one of the tries of the season.

80 min: Luke Metcalf sealed the Warriors win with a well deserved late try.

73 min: Daly Cherry-Evans has also come from the field with a back injury. Cherry-Evans needed to be assisted after being down for some time clutching his lower back.

71 min: Roger Tuivasa-Sheck charged over the tryline to all but seal the win for the Warriors after receiving the ball near the sideline from a flick pass by centre Adam Pompey. Warriors 30-16.

67 min: Tom Trbojevic left the field to receive treatment for hamstring tightness in the Manly dressing room and did not return.

65 min: Sea Eagles prop Jake Trbojevic was sent to the sinbin after repeated infringements by the visitors. Manly have conceded 11 set re-starts - six for ruck infringements and five for offside.

58 min: Cherry-Evans scored one of the season's most spectacular tries after Saab raced down the touchline, kicked ahead and Garrick managed to bat the ball into the in-goal area before it went dead for his captain to score. Warriors 24-16.

The official crowd was announced as 21,212

51 min: Warriors hooker Wayde Egan put paid to thoughts of a Sea Eagles comeback when he made a 40m break after picking up a loose ball from Paseka. Egan was run down by Hopoate and two tackles later he raced over from dummy half. Warriors 24-10.

48 min: Saab put Manly back into the game after scoring in the corner from a Luke Brooks cutout pass. The bunker studied footage closely to determine whether Saab had lost the ball during grounding but could not find evidence of separation to overturn the try. Garrick missed the sideline conversion. Warriors 18-10. 

Half time summary

Errors hurt Manly badly in the first half after a stunning start to the match. Tom Trbojevic scored after just four minutes and the superstar fullback was threatening the defence every time he touched the ball. However, handling errors cost the Sea Eagles more tries and allowed the Warriors to gain momentum. Trbojevic made four first half errors, while a spilled bomb by winger Lehi Hopoate led to a try by Warriors centre Taine Tuaupiki. On the back foot, the Sea Eagles have conceded six set re-starts through ruck infringements or being inside the 10m. 

30 min: Rookie centre Ali Leiataua puts the home side further ahead after running onto a short pass from Metcalf close to the Sea Eagles line. Metcalfe converted. Warriors 18-6.

27 min: The Warriors have hit the lead after winger Taine Tuaupiki stepped inside after receiving a long pass from Metcalf, beat two defenders and then accelerated between Jazz Tevaga and Taniela Paseka to score. Warriors 12-6. 

20 min: Halves Luke Metcalf and Chanel Harris-Tevita combined to level the scores, with Metcalf putting Harris-Tavita over for the first try of teh season at home before converting from out wide. Warriors 6 Sea Eagles 6. 

18 min: Trbojevic is tearing the Warriors apart but the Sea Eagles have blown back-to-back scoring chances after knocking on an inside pass from Lehi Hopoate and throwing a forward pass to centre Faulalo. 

10 min: Garrick lands a penalty goal after Warriors superstar Roger Tuivasa-Sheck was penalised for a high tackle on the Manly centre. Sea Eagles 6-0.

4 min: Tom Trbojevic picked up where he left off last week, scoring the first try after shifting the ball to the right through Reuben Garrick to Jason Saab and backing up inside to score. Garrick missed the conversion. Sea Eagles 4-0.